Antimicrobial Analysis of Biosynthesized Lectin-Conjugated Gold Nanoparticles
نویسندگان
چکیده
To enhance the bioactivity of molecules through nanoparticles is being tested which has potential use in sustained-release drug delivery systems and to therapeutic effectiveness drugs. Our current investigation s conjugate lectin that a gold nanoparticle (GNP) surface without disturbing bioactive properties enhances antibacterial activity lectin. Au-lectin were checked for their hemagglutination activity, characterized by transmission electron microscopy (TEM) UV-visible spectrophotometer. The effect lectin, Au salt nanoparticle, conjugated was estimated Kirby-Bauer disc method; MICs determined microbroth dilution compared with ciprofloxacin. These tests done using known species bacterial strain multidrug resistant. improved fourfold after purification. Lectin combined had significant on inhibition growth. No differences observed zone diameters from killed bacteria its supernatant towards any organisms. Lectin-conjugated particles showed good efficacy as antimicrobial agents nanoparticle-killed work against viable population same bacterium and/or other too.
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ژورنال
عنوان ژورنال: Adsorption Science & Technology
سال: 2022
ISSN: ['2048-4038', '0263-6174']
DOI: https://doi.org/10.1155/2022/8187260